Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.45 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829403 | 0.86 | NR1H2 (0.49) | NR1H2NR1H3RIPK1GPR119HCRTR2 | |
| SCHEMBL14829637 | 0.86 | NR1H2 (0.49) | NR1H2NR1H3RIPK1GPR119HCRTR2 | |
| SCHEMBL13749174 | 0.86 | NR1H2 (0.49) | NR1H2NR1H3RIPK1GPR119HCRTR2 | |
| SCHEMBL3188043 | 0.81 | NR1H2 (0.56) | NR1H2NR1H3RIPK1HTRA1RORC | |
| SCHEMBL3188035 | 0.81 | NR1H2 (0.56) | NR1H2NR1H3RIPK1HTRA1RORC | |
| SCHEMBL12668388 | 0.81 | NR1H2 (0.56) | NR1H2NR1H3RIPK1HTRA1RORC | |
| SCHEMBL27504373 | 0.78 | RIPK1 (0.66) | NR1H2NR1H3RIPK1RORCGPR119 | |
| SCHEMBL19471092 | 0.78 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL17881957 | 0.78 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL17881877 | 0.78 | RIPK1 (0.64) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2930173-B1 | METHOD FOR PREPARING CABAZITAXEL FROM 10-DEACETYLBACCATIN III IN HIGH YIELD, AND NOVEL INTERMEDIATE THEREFOR | SAMYANG BIOPHARMACEUTICALS (KR) | 2019-04-10 | — | — | EP | disclosed |