SCHEMBL20879602

SCHEMBL20879602

N[C@@H](CCCCNC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(O)O)CC1)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14675293 0.95 FOLH1 (0.64) FOLH1
SCHEMBL14675561 0.94 FOLH1 (0.62) FOLH1
SCHEMBL19403116 0.84 FOLH1 (0.73) FOLH1
SCHEMBL17119753 0.83 FOLH1 (0.75) FOLH1
SCHEMBL25575645 0.83 FOLH1 (0.75) FOLH1
SCHEMBL11930724 0.82 FOLH1 (0.67) FOLH1
SCHEMBL25574479 0.82 FOLH1 (0.71) FOLH1
SCHEMBL18655464 0.82 FOLH1 (0.70) FOLH1
SCHEMBL23790343 0.82 FOLH1 (0.67) FOLH1
SCHEMBL16781668 0.81 FOLH1 (0.73) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739316-B1 RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS MOLECULAR INSIGHT PHARM INC (US) 2019-04-10 EP disclosed