SCHEMBL20879877

SCHEMBL20879877

Ic1cccc2c1Oc1ccccc1N2

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.59
DHODH Q02127 1/20 0.39
AHR P35869 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HTR2B P41595 2/20 0.34
HTR7 P34969 1/20 0.34
PARP1 P09874 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579624 0.79
SCHEMBL31191633 0.77 ALOX5 (0.59) ALOX5DHODHAHRMEN1KMT2A
SCHEMBL5119557 0.77 ALOX5 (0.59) ALOX5DHODHAHRMEN1KMT2A
SCHEMBL31191635 0.77 ALOX5 (0.59) ALOX5DHODHMEN1KMT2AGAA
SCHEMBL7558801 0.77 ALOX5 (0.59) ALOX5DHODHAHRMEN1KMT2A
SCHEMBL19745771 0.77 ALOX5 (0.59) ALOX5DHODHAHRMEN1KMT2A
SCHEMBL11537969 0.77 ALOX5 (0.59) ALOX5DHODHAHRMEN1KMT2A
SCHEMBL10558860 0.77 ALOX5 (0.59) ALOX5DHODHMEN1KMT2AGAA
Phenoxazine SCHEMBL6310178 0.76 ALOX5 (1.00) ALOX5DHODHMEN1KMT2AGAA
Phenoxazine SCHEMBL29355714 0.76 ALOX5 (1.00) ALOX5DHODHMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247771-B1 PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2020-06-10 EP disclosed
EP-3247770-B1 ORGANIC MOLECULES, IN PARTICULAR, FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2019-04-10 EP disclosed