Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849362 | 1.00 | LMNA (0.51) | LMNAALDH1A1KMT2AALOX15SIGMAR1 | |
| SCHEMBL23488936 | 0.91 | KMT2A (0.54) | LMNAALDH1A1KMT2ASIGMAR1TSHR | |
| SCHEMBL20879985 | 0.91 | KMT2A (0.54) | LMNAALDH1A1KMT2ASIGMAR1TSHR | |
| SCHEMBL20879944 | 0.85 | LMNA (0.45) | LMNAALDH1A1PAOXNAAAGRM4 | |
| SCHEMBL22415477 | 0.85 | LMNA (0.45) | LMNAALDH1A1PAOXNAAAGRM4 | |
| SCHEMBL18588461 | 0.85 | LMNA (0.48) | LMNAALDH1A1KMT2AALOX15SIGMAR1 | |
| SCHEMBL25139930 | 0.85 | LMNA (0.48) | LMNAALDH1A1KMT2AALOX15SIGMAR1 | |
| SCHEMBL18588459 | 0.85 | LMNA (0.48) | LMNAALDH1A1KMT2AALOX15SIGMAR1 | |
| SCHEMBL24098243 | 0.83 | LMNA (0.47) | LMNAALDH1A1KMT2AALOX15SIGMAR1 | |
| SCHEMBL23252220 | 0.82 | LMNA (0.46) | LMNAALDH1A1KMT2AALOX15SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782649-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | Ascendis Pharma A/S (DK) | 2021-02-24 | — | — | EP | disclosed |
| EP-2237799-B1 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2019-04-10 | — | — | EP | disclosed |