Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20883035 | 0.90 | ALDH1A1 (0.65) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL2957547 | 0.74 | HTT (0.56) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL2953334 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL616835 | 0.73 | ALDH1A1 (0.78) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL2959776 | 0.73 | POLB (0.63) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL2959409 | 0.73 | KMT2A (0.65) | ALDH1A1HPGDPOLBLMNAPKM | |
| SCHEMBL10722295 | 0.73 | KMT2A (0.84) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL2962722 | 0.72 | KDM4E (0.70) | HTTPOLBLMNAPKMMAPT | |
| SCHEMBL2963614 | 0.71 | CHRM1 (0.58) | ALDH1A1HPGDHTTPOLBLMNA | |
| SCHEMBL2954368 | 0.71 | MEN1 (0.56) | ALDH1A1HPGDPOLBPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019070709-A1 | COMPOUNDS FOR TREATING OR PREVENTING FLAVIVIRUS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-11 | — | — | WO | disclosed |