Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 13/20 | 0.45 |
| ▸ | CDK2 | P24941 | 13/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 13/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877486 | 1.00 | CCNE1 (0.45) | CCNE1CDK2CDK5CDK5R1CTSK | |
| SCHEMBL20877547 | 1.00 | CCNE1 (0.45) | CCNE1CDK2CDK5CDK5R1CTSK | |
| SCHEMBL20877375 | 0.92 | CCNE1 (0.47) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL30693385 | 0.81 | CCNE1 (0.47) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL22494667 | 0.80 | CCNE1 (0.50) | CCNE1CDK2CDK5CDK5R1USP30 | |
| SCHEMBL20877549 | 0.80 | CCNE1 (0.50) | CCNE1CDK2CDK5CDK5R1USP30 | |
| SCHEMBL20877548 | 0.80 | CCNE1 (0.50) | CCNE1CDK2CDK5CDK5R1USP30 | |
| SCHEMBL24514748 | 0.79 | UCHL1 (0.58) | CCNE1CDK2CDK5USP30CNR2 | |
| SCHEMBL20877424 | 0.79 | CCNE1 (0.49) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL20877551 | 0.79 | CCNE1 (0.49) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692028-B1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 30 | FORMA THERAPEUTICS INC (US) | 2023-04-26 | — | — | EP | disclosed |
| WO-2019071073-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 30 | FORMA THERAPEUTICS, INC. (US) | 2019-04-11 | — | — | WO | disclosed |