SCHEMBL20887327

SCHEMBL20887327

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)C(F)(F)F)cnc3n2C)nc2cc(C3(C#N)CC3)ccn12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30585590 0.94 POLB (0.36) POLB
SCHEMBL20887107 0.94 POLB (0.36) POLB
SCHEMBL20887322 0.87 MEN1 (0.32) —
SCHEMBL20887326 0.87 — —
SCHEMBL23353553 0.86 PIK3CD (0.33) POLB
SCHEMBL23353551 0.85 ALDH1A1 (0.34) POLB
SCHEMBL20887324 0.85 — —
SCHEMBL20887328 0.84 CYP1A2 (0.32) —
SCHEMBL20887325 0.83 KDM4E (0.35) —
SCHEMBL24576364 0.82 ALDH1A1 (0.31) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10981935-B2 Heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2021-04-20 — — US disclosed
US-20200291043-A1 HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-09-17 — — US disclosed
WO-2019068572-A1 DERIVATIVES OF HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2019-04-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200291043-A1 HETEROCYCLE DERIVATIVES AS PESTICIDES DDT, CBR3, CBR1 POLB 4605/4885
US-10981935-B2 Heterocycle derivatives as pesticides DDT, CBR3, CBR1 POLB 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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