Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.72 |
| ▸ | ABL1 | P00519 | 4/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.72 |
| ▸ | KIT | P10721 | 1/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.59 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804150 | 0.85 | PIK3CG (0.80) | DYRK1APIK3CGPIK3CACYP3A4NPC1 | |
| SCHEMBL10170616 | 0.85 | DYRK1A (1.00) | DYRK1APIK3CGPIK3CACYP3A4NPC1 | |
| SCHEMBL30593693 | 0.84 | ABL1 (1.00) | ABL1PDGFRAKIT | |
| SCHEMBL20855238 | 0.84 | ABL1 (1.00) | ABL1PDGFRAKIT | |
| SCHEMBL20855185 | 0.84 | ABL1 (1.00) | ABL1PDGFRAKIT | |
| SCHEMBL29078597 | 0.84 | ABL1 (1.00) | ABL1PDGFRAKIT | |
| SCHEMBL1621800 | 0.82 | ABL1 (1.00) | ABL1PDGFRAKITPIK3CGPIK3CA | |
| SCHEMBL3716998 | 0.81 | PIK3CG (0.79) | DYRK1APIK3CGPIK3CACYP3A4NPC1 | |
| SCHEMBL20855132 | 0.79 | ABL1 (1.00) | ABL1PDGFRAKITPIK3CGRAB9A | |
| SCHEMBL20887521 | 0.79 | PIK3CG (0.70) | DYRK1AABL1PDGFRAKITPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019070093-A1 | BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS | 1ST Biotherapeutics, Inc. (KR) | 2019-04-11 | — | — | WO | disclosed |