Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19279436 | 1.00 | LMNA (0.55) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL20888034 | 1.00 | LMNA (0.55) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL20888040 | 0.91 | LMNA (0.49) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL20888041 | 0.91 | LMNA (0.49) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL19279511 | 0.88 | KMT2A (0.59) | LMNAALDH1A1KMT2AMEN1ATM | |
| SCHEMBL19279510 | 0.88 | KMT2A (0.59) | LMNAALDH1A1KMT2AMEN1ATM | |
| SCHEMBL20888249 | 0.88 | KMT2A (0.59) | LMNAALDH1A1KMT2AMEN1ATM | |
| SCHEMBL20888269 | 0.88 | KMT2A (0.59) | LMNAALDH1A1KMT2AMEN1ATM | |
| SCHEMBL22423030 | 0.87 | LMNA (0.50) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL20888272 | 0.86 | LMNA (0.47) | LMNAAKR1B10AKR1B1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209639-B1 | COMPOUNDS AS ANTI-MALARIALS AND THEIR PROCESS OF PREPARATION | COUNCIL SCIENT IND RES (IN) | 2020-09-16 | — | — | EP | disclosed |
| US-20190106380-A1 | Aromatic Derivatives As Anti-Malarial | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106380-A1 | Aromatic Derivatives As Anti-Malarial | TYR, CYP3A43, H1-3 | LMNA 2961/4885AKR1B10 1004/4885AKR1B1 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.