Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.75 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.75 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451743 | 1.00 | STING1 (0.75) | STING1TBK1ENPP1 | |
| SCHEMBL19451742 | 1.00 | STING1 (0.75) | STING1TBK1ENPP1 | |
| SCHEMBL20075967 | 0.92 | STING1 (0.68) | STING1TBK1ENPP1 | |
| SCHEMBL19451865 | 0.92 | STING1 (0.76) | STING1TBK1ENPP1 | |
| SCHEMBL24467557 | 0.92 | STING1 (0.76) | STING1TBK1ENPP1 | |
| SCHEMBL28597027 | 0.89 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL19451477 | 0.89 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL29702099 | 0.89 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL24467628 | 0.89 | STING1 (0.69) | STING1TBK1ENPP1 | |
| SCHEMBL19451797 | 0.89 | STING1 (0.78) | STING1TBK1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377440-B2 | Modulators of stimulator of interferon genes (STING) | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-07-05 | — | — | US | disclosed |
| US-20200291001-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-09-17 | — | — | US | disclosed |
| WO-2019069270-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377440-B2 | Modulators of stimulator of interferon genes (STING) | STING1, IRF3, IFNAR1 | STING1 1/4885TBK1 10/4885ENPP1 3246/4885 |
| US-20200291001-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, IFNAR1 | STING1 1/4885TBK1 10/4885ENPP1 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.