SCHEMBL20892745

SCHEMBL20892745

Cc1cc(C)cc(S(=O)(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](Cc2cccc(F)c2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCC(=O)O)C(N)=O)c1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 15/20 0.56
▸ CCKAR P32238 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14478158 0.98 CCKBR (0.54) CCKBRCCKAR
SCHEMBL14478159 0.95 CCKBR (0.57) CCKBRCCKAR
SCHEMBL14478115 0.95 CCKBR (0.57) CCKBRCCKAR
SCHEMBL14478118 0.94 CCKBR (0.57) CCKBRCCKAR
SCHEMBL14478155 0.92 CCKBR (0.56) CCKBRCCKAR
SCHEMBL20892743 0.92 CCKBR (0.55) CCKBRCCKAR
SCHEMBL20892784 0.92 CCKBR (0.55) CCKBRCCKAR
SCHEMBL14478107 0.91 CCKBR (0.55) CCKBRCCKAR
SCHEMBL14478125 0.91 CCKBR (0.55) CCKBRCCKAR
SCHEMBL14478117 0.91 CCKBR (0.57) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190106460-A1 BINDING INHIBITORS OF THE BETA. TRANSDUCIN REPEAT-CONTAINING PROTEIN BRADLEY MARK (GB) 2019-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190106460-A1 BINDING INHIBITORS OF THE BETA. TRANSDUCIN REPEAT-CONTAINING PROTEIN TARDBP, DDB1, EPS15 CCKBR 4467/4885CCKAR 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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