SCHEMBL208934

SCHEMBL208934

C=C(CCC(F)(F)C(F)(F)C(F)F)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.36
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005511 0.89 TET2 (0.34) TET2TET3TET1
SCHEMBL5529391 0.87 TSHR (0.35) TET2
SCHEMBL2976485 0.86 TSHR (0.37) TET2
SCHEMBL5526626 0.86 TSHR (0.37) TET2
SCHEMBL16240728 0.86 TSHR (0.37) TET2
SCHEMBL2968317 0.86 TSHR (0.37) TET2
SCHEMBL1005480 0.86 TSHR (0.37) TET2
SCHEMBL5191388 0.80 TET2 (0.47) TET2TET3TET1GRIK1GRIK2
SCHEMBL210760 0.80 TET2 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL261639 0.79 TET2 (0.45) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2443486-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-03-01 EP claimed
US-8133960-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US claimed
US-20090173643-A1 Packaging Solutions LAI YU-CHIN 2009-07-09 US claimed
US-20090156708-A1 BIOMEDICAL DEVICES SOLTA MEDICAL IRELAND LIMITED (IE) 2009-06-18 US claimed
EP-1465931-B1 AZETIDINIUM MODIFIED POLYMERS AND FABRIC TREATMENT COMPOSITION UNILEVER PLC (GB) 2007-08-01 EP claimed
US-6610278-B2 Hardness not greater than 75 as measured by an Asker rubber-hardness tester type C1L; a porosity of at least 0.4; and an impact resistance of at least 5; excellent skin feel upon use and is not easily broken. KAO CORPORATION (JP) 2003-08-26 US claimed
US-20020028220-A1 POWDER-BASED SOLID COSMETIC COMPOSITION AND PREPARATION PROCESS THEREOF KAO CORPORATION (JP) 2002-03-07 US claimed
EP-0449274-B1 Fluoroacrylic polymer having lubricating effect and thermoplastic resin composition comprising same MITSUBISHI RAYON CO (JP) 1995-10-04 EP claimed
EP-0201246-B1 LIGHT TRANSMITTING FIBER MITSUBISHI RAYON CO., LTD. (JP) 1991-03-20 EP claimed
US-20230411335-A1 THERMOSETTING RESIN COMPOSITION, SEMICONDUCTOR DEVICE AND ELECTRICAL/ELECTRONIC COMPONENT KYOCERA CORPORATION (JP) 2023-12-21 US disclosed
US-11784153-B2 Thermosetting resin composition, semiconductor device, and electrical/electronic component KYOCERA CORPORATION (JP) 2023-10-10 US disclosed
EP-3178856-B1 COMPOSITION FOR THE PRODUCTION OF PRESSURE-SENSITIVE ADHESIVES TESA SE (DE) 2020-03-25 EP disclosed
EP-3128540-B1 THERMOSETTING RESIN COMPOSITION, SEMICONDUCTOR DEVICE AND ELECTRICAL/ELECTRONIC COMPONENT KYOCERA CORP (JP) 2019-06-12 EP disclosed
US-9868846-B2 Curable composition for imprints, patterning method and pattern FUJIFILM CORPORATION (JP) 2018-01-16 US disclosed
EP-0898972-B1 Soft intraocular lens material MENICON CO LTD (JP) 2003-04-09 EP disclosed
US-20020028220-A1 POWDER-BASED SOLID COSMETIC COMPOSITION AND PREPARATION PROCESS THEREOF KAO CORPORATION (JP) 2002-03-07 US disclosed
US-6140438-A FLEXIBLE, ACRYLIC POLYMER COMPRISING CROSSLINKABLE MONOMER UNITS, AROMATIC (METH)ACRYLATE UNITS, ALKYL (METH)ACRYLATE UNITS AND HYDROPHILIC UNITS INCLUDING HYDROXYALKYL ACRYLATE, (METH)ACRYLAMIDES, AND/OR N-VINYL LACTAMS; HAZE-FREE IMPLANTS MENICON CO., LTD. (JP) 2000-10-31 US disclosed
EP-0968705-A1 Powder-based solid cosmetic composition and preparation process thereof Kao Corporation (JP) 2000-01-05 EP disclosed
EP-0898972-A2 Soft intraocular lens material Menicon Co., Ltd. (JP) 1999-03-03 EP disclosed
US-5519070-A FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1996-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028220-A1 POWDER-BASED SOLID COSMETIC COMPOSITION AND PREPARATION PROCESS THEREOF CUTA, C1R, C1S TET2 2138/4885TET3 3913/4885TET1 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.