Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 12/20 | 0.48 |
| ▸ | CDK9 | P50750 | 3/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 11/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | CDK4 | P11802 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.45 |
| ▸ | CDK7 | P50613 | 7/20 | 0.45 |
| ▸ | CCNH | P51946 | 6/20 | 0.45 |
| ▸ | CCND1 | P24385 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318356 | 0.92 | AHR (0.51) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL2317564 | 0.89 | AHR (0.62) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL20895820 | 0.86 | CDK2 (0.51) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL2311792 | 0.86 | KDM4E (0.58) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL18558073 | 0.86 | AHR (0.49) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL3501809 | 0.85 | AHR (0.51) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL2315406 | 0.84 | CDK5 (0.64) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL15010705 | 0.84 | CDK1 (0.54) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL2317298 | 0.83 | AHR (0.50) | AHRCDK2CDK9CCNE1CCNA2 | |
| SCHEMBL21017207 | 0.83 | CDK2 (0.52) | CDK2CDK9CCNE1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350078-B1 | COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS | NOVARTIS AG (CH) | 2019-04-17 | — | — | EP | claimed |