Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.52 |
| ▸ | CDK9 | P50750 | 5/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 13/20 | 0.52 |
| ▸ | CDK4 | P11802 | 12/20 | 0.52 |
| ▸ | CDK7 | P50613 | 12/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 11/20 | 0.52 |
| ▸ | CCNH | P51946 | 11/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.52 |
| ▸ | CCND1 | P24385 | 10/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.52 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.52 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CCNK | O75909 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315371 | 0.90 | CDK2 (0.54) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL25309378 | 0.86 | CDK2 (0.56) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL30518560 | 0.86 | CDK2 (0.56) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL2318356 | 0.86 | AHR (0.51) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL30315420 | 0.85 | CCNK (0.55) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL2311460 | 0.85 | CCNK (0.55) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL30518535 | 0.84 | CCNK (0.64) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL25308297 | 0.84 | CCNK (0.64) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL2310970 | 0.83 | CDK5 (0.53) | CDK2CDK9CDK5CCNA2CCNA1 | |
| SCHEMBL20895840 | 0.83 | AHR (0.49) | CDK2CDK9CDK5CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788476-B1 | COMPOSITIONS AND METHODS FOR ENHANCED GENERATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS | HUTCHINSON FRED CANCER RES (US) | 2019-05-22 | — | — | EP | disclosed |