⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794284 | 0.78 | — | — | |
| SCHEMBL5925818 | 0.74 | — | — | |
| SCHEMBL12618144 | 0.74 | — | — | |
| SCHEMBL508538 | 0.74 | — | — | |
| SCHEMBL29655658 | 0.71 | — | — | |
| SCHEMBL2419335 | 0.71 | — | — | |
| SCHEMBL13222949 | 0.69 | MAPT (0.38) | — | |
| SCHEMBL4635194 | 0.69 | NAPRT (0.48) | — | |
| SCHEMBL30259108 | 0.69 | ALDH1A1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL29259777 | 0.69 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576093-A4 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS INC (US) | 2009-07-08 | — | — | EP | claimed |
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | DYNAMIS THERAPEUTICS, INC. | 2007-03-22 | — | — | US | claimed |
| EP-1753861-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | Dynamis Therapeutics, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1576093-A2 | 3-DEOXYGLUCOSONE AND SKIN | Dynamis Therapeutics, Inc. (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2005079463-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | DYNAMIS THERAPEUTICS, INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-20050159383-A1 | Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) | DYNAMIS THERAPEUTICS, INC. | 2005-07-21 | — | — | US | claimed |
| US-20030219440-A1 | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS, INC. | 2003-11-27 | — | — | US | claimed |
| WO-2003089601-A2 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS, INC. (US) | 2003-10-30 | — | — | WO | claimed |
| CN-118908887-A | Preparation method and intermediate of 2-amino-6-hydroxypyridine compound | 上海凌凯科技股份有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-109535403-B | Preparation method of polyarylate based on 2- (3-carboxyphenyl) -6-hydroxypyridoimidazole | 宁波聚嘉新材料科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-110317323-B | Preparation method of polyarylate based on 2- (3-carboxyl-4-methoxyphenyl) -6-hydroxypyridoimidazole | 浙江甬仑聚嘉新材料有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-110317323-A | The preparation method of polyarylate of the one kind based on 2- (3- carboxyl -4- methoxyphenyl) -6- pyridone and imidazoles | 浙江甬仑聚嘉新材料有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109535403-A | The preparation method of polyarylate of the one kind based on 2- (3- carboxyl phenyl) -6- pyridone and imidazoles | 宁波聚嘉新材料科技有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-101084235-B | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC | 2012-10-17 | — | — | CN | disclosed |
| US-20030219440-A1 | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS, INC. | 2003-11-27 | — | — | US | disclosed |
| WO-2003089601-A2 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS, INC. (US) | 2003-10-30 | — | — | WO | disclosed |
| EP-1175155-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000062626-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2000-10-26 | — | — | WO | disclosed |
| WO-1993013775-A1 | DIAMINOPYRIDINE COMPOUNDS FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | THE ROCKEFELLER UNIVERSITY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5221683-A | Inhibiting advanced clycosylation of target protein | THE ROCKEFELLER UNIVERSITY (US) | 1993-06-22 | — | — | US | disclosed |