Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.32 |
| ▸ | CPS1 | P31327 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291353 | 0.75 | MC4R (0.31) | — | |
| SCHEMBL15536669 | 0.64 | PROKR1 (0.32) | — | |
| SCHEMBL28292803 | 0.64 | SRD5A2 (0.36) | — | |
| SCHEMBL28291347 | 0.62 | SRD5A2 (0.35) | — | |
| SCHEMBL24702127 | 0.61 | DRD1 (0.60) | — | |
| SCHEMBL28091439 | 0.61 | TAAR1 (0.47) | PKMTAAR1NFE2L2 | |
| SCHEMBL17009613 | 0.60 | KDM4E (0.51) | — | |
| SCHEMBL17713023 | 0.60 | GRIN2D (0.44) | EGFR | |
| SCHEMBL954134 | 0.60 | ERN1 (0.50) | PKMTAAR1 | |
| SCHEMBL14720435 | 0.58 | MCHR1 (0.37) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019072978-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-04-18 | — | — | WO | disclosed |