Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113179 | 0.81 | NPC1 (0.33) | KDM4EMAPK1RAB9ANPC1 | |
| SCHEMBL14468186 | 0.73 | — | — | |
| SCHEMBL24447 | 0.72 | — | — | |
| SCHEMBL19310541 | 0.66 | — | — | |
| SCHEMBL6128389 | 0.66 | — | — | |
| SCHEMBL3105012 | 0.66 | — | — | |
| SCHEMBL5256551 | 0.65 | TRPV1 (0.43) | MAPTHIF1ARAB9ANPC1KMT2A | |
| SCHEMBL24906139 | 0.64 | KDM4E (0.40) | KDM4EMAPK1APEX1POLBMAPT | |
| SCHEMBL23974340 | 0.64 | KDM4E (0.40) | KDM4EMAPK1APEX1POLBMAPT | |
| SCHEMBL29044988 | 0.64 | HDAC6 (0.47) | ALDH1A1CA1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812044-B2 | Anticancer agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-12 | — | — | US | claimed |
| EP-2094246-B1 | SUSTAINED-RELEASE COMPOSITION AND METHOD FOR PRODUCING THE SAME | TAKEDA PHARMACEUTICALS CO (JP) | 2020-04-01 | — | — | EP | disclosed |
| US-9713595-B2 | Sustained-release composition and method for producing the same | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2017-07-25 | — | — | US | disclosed |
| US-20170165204-A1 | SUSTAINED-RELEASE COMPOSITION AND METHOD FOR PRODUCING THE SAME | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-06-15 | — | — | US | disclosed |
| US-9617303-B2 | Sustained-release composition and method for producing the same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-04-11 | — | — | US | disclosed |
| EP-1466596-B1 | MICROSPHERE AND METHOD FOR PRODUCTION THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-08-31 | — | — | EP | disclosed |
| EP-1297850-B1 | MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES | TAKEDA PHARMACEUTICAL (JP) | 2015-08-19 | — | — | EP | disclosed |
| US-20150080322-A1 | SUSTAINED-RELEASE COMPOSITION AND METHOD FOR PRODUCING THE SAME | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-03-19 | — | — | US | disclosed |
| US-8927016-B2 | Producing a sustained-release preparation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-01-06 | — | — | US | disclosed |
| US-8921326-B2 | Sustained-release composition and method for producing the same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-30 | — | — | US | disclosed |
| EP-1297850-A1 | MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES | Takeda Chemical Industries, Ltd. (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-1049458-B1 | LYOPHILIZATION METHOD FOR SUSTAINED-RELEASE PREPARATIONS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2003002092-A2 | CONTROLLED RELEASE COMPOSITION COMPRISING LACTIC ACID POLYMER AND HYDROXYNAPHTHOIC ACID, AND METHOD OF PRODUCING THE SAME | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-09 | — | — | WO | disclosed |
| EP-1197208-A1 | SUSTAINED RELEASE COMPOSITIONS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |
| EP-1158014-A1 | PROCESS FOR PRODUCING POLYMER | Takeda Chemical Industries, Ltd. (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-1136079-A1 | AGENTS FOR RETARDING CHANGE OF HORMONE-DEPENDENT CANCER INTO HORMONE-INDEPENDENT CANCER | Takeda Chemical Industries, Ltd. (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-1049458-A1 | LYOPHILIZATION METHOD FOR SUSTAINED-RELEASE PREPARATIONS | Takeda Chemical Industries, Ltd. (JP) | 2000-11-08 | — | — | EP | disclosed |
| EP-1048301-A1 | SUSTAINED RELEASE COMPOSITIONS, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999037288-A1 | LYOPHILIZATION METHOD FOR SUSTAINED-RELEASE PREPARATIONS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-29 | — | — | WO | disclosed |
| WO-1998032423-A1 | SUSTAINED-RELEASE MICROSPHERES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-30 | — | — | WO | disclosed |