⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749784 | 0.88 | ALDH1A1 (0.38) | — | |
| SCHEMBL5280889 | 0.76 | — | — | |
| SCHEMBL6128389 | 0.76 | — | — | |
| SCHEMBL14468186 | 0.75 | — | — | |
| SCHEMBL30262375 | 0.75 | — | — | |
| SCHEMBL20909482 | 0.73 | ALDH1A1 (0.55) | — | |
| SCHEMBL25885686 | 0.73 | KDM4E (0.44) | — | |
| SCHEMBL3468250 | 0.73 | CA1 (0.32) | — | |
| SCHEMBL24447 | 0.73 | — | — | |
| SCHEMBL30171078 | 0.72 | CHRM3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124698-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-19 | — | — | WO | disclosed |
| CN-120118001-A | Aerobic nitriding method for olefin compounds | 北京大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-115515962-B | Fused isoxazoline derivatives and their use as herbicides | 巴斯夫欧洲公司 | 2025-04-29 | — | — | CN | disclosed |
| US-20230174551-A1 | CONDENSED ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2023-06-08 | — | — | US | disclosed |
| CN-115515962-A | Fused isoxazoline derivatives and their use as herbicides | 巴斯夫欧洲公司 | 2022-12-23 | — | — | CN | disclosed |
| US-20210292334-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2021-09-23 | — | — | US | disclosed |
| US-7803837-B2 | 4-oxo-4,5-dihydro-furan-2-carboxylic acid derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20070161701-A1 | 4-oxo-4,5-dihydro-furan-2-carboxylic acid derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. | 2007-07-12 | — | — | US | disclosed |
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4330650-A | HAVING MAGNESIUM COMPONENTS, TITANIUM COMPONENTS, ORGANOALUMINUM COMPONENTS AND HETEROCYCLIC CARBOXYLIC ESTER ELECTRON DONOR COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-05-18 | — | — | US | disclosed |
| US-4255280-A | ORGANOMAGNESIUM, CHLOROSILANE, TITANIUM, ORGANOMETALLIC AND HETEROCYCLIC ESTER COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |