Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305690 | 0.92 | MCL1 (0.41) | PLGHRH2HRH1MCL1PPARG | |
| SCHEMBL16306192 | 0.90 | S1PR5 (0.41) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL16305927 | 0.86 | MCL1 (0.40) | PLGHRH2HRH1MCL1PPARG | |
| SCHEMBL16305664 | 0.85 | ACE (0.42) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL22384286 | 0.85 | PPARG (0.39) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL16305673 | 0.85 | ACE (0.42) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL16305672 | 0.85 | ACE (0.42) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL16305678 | 0.85 | ACE (0.42) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL16305676 | 0.84 | PPARG (0.42) | PLGHRH2HRH1PPARGPPARA | |
| SCHEMBL16294995 | 0.83 | S1PR5 (0.45) | PLGHRH2HRH1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259823-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2019-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259823-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | PLG 2930/4885HRH2 469/4885HRH1 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.