Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 19/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998247 | 1.00 | F11 (0.54) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL18478438 | 1.00 | F11 (0.54) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL16998249 | 0.91 | F11 (0.51) | F11 | |
| SCHEMBL18476270 | 0.91 | F11 (0.51) | F11 | |
| SCHEMBL27045629 | 0.88 | F11 (0.52) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL20901311 | 0.88 | F11 (0.56) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL24092125 | 0.87 | F11 (0.54) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL16998248 | 0.87 | F11 (0.54) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL16989245 | 0.87 | F11 (0.70) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL27129861 | 0.87 | F11 (0.70) | F11TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259785-B2 | Therapeutic compounds and compositions | EXITHERA PHARMACEUTICALS, INC. (US) | 2019-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259785-B2 | Therapeutic compounds and compositions | KLK5, KLKB1, KLK2 | F11 17/4885TPSAB1 122/4885TPSD1 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.