SCHEMBL2090168

SCHEMBL2090168

OCc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2A6 P11509 2/20 0.36
PNMT P11086 1/20 0.36
AHR P35869 2/20 0.34
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
AR P10275 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
RORC P51449 1/20 0.31
IDO1 P14902 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
CLCN2 P51788 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522436 0.89 APOBEC3G (0.36) CYP2A6PNMTTSHRAPOBEC3G
SCHEMBL24823683 0.83 CYP2A6 (0.41) CYP3A4MAPK1CYP2A6PNMTAHR
SCHEMBL11301238 0.80 CYP3A4 (0.37) CYP3A4MAPK1CYP2A6PNMTTSHR
SCHEMBL10771987 0.80 MAPK1 (0.42) CYP3A4MAPK1CYP2A6PNMTTSHR
SCHEMBL2361509 0.80 PDCD1 (0.36) CYP3A4MAPK1CYP2A6CYP1A2RORC
SCHEMBL30055353 0.80 CYP3A4 (0.37) CYP3A4MAPK1CYP2A6PNMTTSHR
SCHEMBL28502937 0.79 CYP3A4 (0.46) CYP3A4MAPK1CYP2A6PNMTAHR
SCHEMBL18190544 0.78 CYP3A4 (0.36) CYP3A4MAPK1CYP2A6PNMTTSHR
SCHEMBL4337373 0.78 PDCD1 (0.39) CYP3A4MAPK1CYP2A6PNMTTSHR
SCHEMBL18728627 0.78 CYP3A4 (0.31) CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108745222-B Anti-sedimentation type microreactor and synthesis system 华北电力大学 2023-09-01 CN disclosed
WO-2022271182-A1 HALOGENATED POLYURETHANE COATING COMPOSITIONS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-12-29 WO disclosed
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
EP-3040332-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-06-03 EP disclosed
EP-2990404-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-05-27 EP disclosed
CN-110072698-A Multilayer film and its sack 陶氏环球技术有限责任公司 2019-07-30 CN disclosed
CN-109195998-A Polyolefin blends comprising crystalline block composites for PVC-free wear layers 陶氏环球技术有限责任公司 2019-01-11 CN disclosed
EP-3061756-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-11-14 EP disclosed
CN-105593286-B Compatibilized Polyolefin Blends 陶氏环球技术有限责任公司 2018-10-09 CN disclosed
WO-2000026447-A1 INCORPORATION OF ORGANIC ANTI-MICROBIALS INTO FIBRES DURING A FIBRE SPINNING PROCESS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO disclosed
EP-0937812-A2 Process for the treatment of nonwovens with antimicrobial agents Ciba SC Holding AG (CH) 1999-08-25 EP disclosed
EP-0914085-A2 CONCENTRATED LIQUID ACCUMULATIONS COMPRISING A MICROBICIDALLY ACTIVE INGREDIENT Ciba SC Holding AG (CH) 1999-05-12 EP disclosed
EP-0908553-A2 Process for the treatment of textile materials with an antimicrobial agent Ciba SC Holding AG (CH) 1999-04-14 EP disclosed
WO-1997046218-A2 CONCENTRATED LIQUID FORMULATIONS COMPRISING A MICROBICIDALLY ACTIVE INGREDIENT CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO disclosed
CN-1154728-A Method for dyeing polytrimethylene terephthalate fibres and use of the dyed fibres DEGUSSA (DE) 1997-07-16 CN disclosed
EP-0777717-A2 SURFACE-ACTIVE FORMULATIONS Ciba SC Holding AG (CH) 1997-06-11 EP disclosed
EP-0719244-A1 PROCESS OF PREPARING 2,3,5-TRIHALOBENZALDEHYDE THE WELLCOME FOUNDATION LIMITED (GB) 1996-07-03 EP disclosed
WO-1996006153-A2 SURFACE-ACTIVE FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-02-29 WO disclosed
WO-1995007877-A1 PROCESS OF PREPARING 2,3,5-TRIHALOBENZALDEHYDE THE WELLCOME FOUNDATION LIMITED (GB) 1995-03-23 WO disclosed