⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793313 | 1.00 | ADH1B (0.42) | — | |
| SCHEMBL330200 | 1.00 | ADH1B (0.42) | — | |
| SCHEMBL7980855 | 1.00 | ADH1B (0.42) | — | |
| SCHEMBL20594191 | 1.00 | ADH1B (0.42) | — | |
| SCHEMBL11791711 | 1.00 | ADH1B (0.42) | — | |
| SCHEMBL330189 | 1.00 | — | — | |
| SCHEMBL20998 | 0.96 | — | — | |
| SCHEMBL22101 | 0.89 | — | — | |
| SCHEMBL8765 | 0.81 | — | — | |
| SCHEMBL3156756 | 0.78 | CHRM5 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5133 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-06-20 | — | — | US | claimed |
| CN-117924243-A | Quinoline derivative, pharmaceutical composition and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | claimed |
| EP-4313943-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-02-07 | — | — | EP | claimed |
| CN-117229205-A | Preparation method and pharmaceutical application of phenyl acrylamide RHbDD1 inhibitor | 中国医学科学院基础医学研究所 | 2023-12-15 | — | — | CN | claimed |
| CN-111655685-B | Thiophene derivative and use thereof | 藤本株式会社 | 2023-11-17 | — | — | CN | claimed |
| CN-117043140-A | Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances | 拜耳公司 | 2023-11-10 | — | — | CN | claimed |
| CN-112010844-B | Preparation method and application of N- (pyrimidine-2-yl) coumarin-7-amine derivative as protein kinase inhibitor | 中国药科大学 | 2023-07-25 | — | — | CN | claimed |
| CN-116354931-A | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-3744719-B1 | THIOPHENE DERIVATIVE AND USE THEREOF | FUJIMOTO CO LTD (JP) | 2023-06-07 | — | — | EP | claimed |
| CN-113024563-B | Pyrimido five-membered heterocyclic compound or pharmaceutically acceptable salt and isomer thereof, and preparation method, pharmaceutical composition and application thereof | 药康众拓(江苏)医药科技有限公司 | 2023-01-03 | — | — | CN | claimed |
| EP-0244836-A2 | Tripeptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-11 | — | — | EP | claimed |
| US-4526786-A | N-Substituted phenyl-5-aminomethyl oxazolidinones and their method of use | DELALANDE S.A. (FR) | 1985-07-02 | — | — | US | claimed |
| EP-0142040-A2 | Substituted pyrimidines | BAYER AG (DE) | 1985-05-22 | — | — | EP | claimed |
| US-4515787-A | Steroids | ROUSSEL UCLAF (FR) | 1985-05-07 | — | — | US | claimed |
| US-4435415-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1984-03-06 | — | — | US | claimed |
| US-4413001-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1983-11-01 | — | — | US | claimed |
| US-4372967-A | ENZYME INHIBITORS, ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1983-02-08 | — | — | US | claimed |
| US-4348393-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-09-07 | — | — | US | claimed |
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | claimed |
| US-4273767-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | claimed |