Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815694 | 0.98 | TSHR (0.43) | TSHRTRPA1ESR2NR1I3LMNA | |
| SCHEMBL16730136 | 0.87 | — | — | |
| SCHEMBL16750985 | 0.87 | — | — | |
| SCHEMBL180095 | 0.87 | — | — | |
| Cyclohexane SCHEMBL7502003 | 0.85 | TSHR (0.38) | TSHRTRPA1ESR2NR1I3LMNA | |
| SCHEMBL112236 | 0.85 | ESR2 (0.40) | TSHRESR2NR1I3LMNAGPBAR1 | |
| Cyclobutanol SCHEMBL8087692 | 0.83 | TSHR (0.36) | TSHRTRPA1ESR2 | |
| Cyclohexanol SCHEMBL596771 | 0.83 | TSHR (0.50) | TSHRTRPA1ESR2CYP2C19HSD17B10 | |
| Cyclohexanol SCHEMBL595842 | 0.83 | TSHR (0.50) | TSHRTRPA1ESR2CYP2C19HSD17B10 | |
| SCHEMBL7115325 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623432-A1 | COMPOSITION | Jotun A/S (NO) | 2020-03-18 | — | — | EP | disclosed |
| EP-3470482-A1 | COMPOSITION | Jotun A/S (NO) | 2019-04-17 | — | — | EP | disclosed |
| EP-3470481-A1 | COMPOSITION | Jotun A/S (NO) | 2019-04-17 | — | — | EP | disclosed |