Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730136 | 0.92 | — | — | |
| SCHEMBL16750985 | 0.92 | — | — | |
| SCHEMBL180095 | 0.92 | — | — | |
| SCHEMBL112236 | 0.89 | ESR2 (0.40) | TSHRESR2NR1I3SHBGLMNA | |
| SCHEMBL9815694 | 0.87 | TSHR (0.43) | TSHRESR2NR1I3SHBGLMNA | |
| SCHEMBL20902010 | 0.85 | TSHR (0.41) | TSHRESR2NR1I3SHBGLMNA | |
| Cyclohexanol SCHEMBL596771 | 0.82 | TSHR (0.50) | TSHRESR2CYP2C19HSD17B10HSD11B1 | |
| Cyclohexanol SCHEMBL595842 | 0.82 | TSHR (0.50) | TSHRESR2CYP2C19HSD17B10HSD11B1 | |
| SCHEMBL4147445 | 0.81 | AKR1B10 (0.31) | ESR2 | |
| Cyclobutanol SCHEMBL8087692 | 0.77 | TSHR (0.36) | TSHRESR2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865461-B1 | PROCESS FOR THE PRODUCTION OF RIGID POLYURETHANE FOAMS IN THE PRESENCE OF HYDROCARBON BLOWING AGENTS | HUNTSMAN INT LLC (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-0865461-A1 | PROCESS FOR THE PRODUCTION OF RIGID POLYURETHANE FOAMS IN THE PRESENCE OF HYDROCARBON BLOWING AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021764-A1 | PROCESS FOR THE PRODUCTION OF RIGID POLYURETHANE FOAMS IN THE PRESENCE OF HYDROCARBON BLOWING AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-06-19 | — | — | WO | disclosed |