SCHEMBL20903633

SCHEMBL20903633

C1=Cc2c(c3ccccc3n2-c2ccc(Oc3ccc(C4(c5ccc(Oc6ccc(-n7c8ccccc8c8ccccc87)cc6)cc5)c5ccccc5-c5ccccc54)cc3)cc2)CC1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ OPRK1 P41145 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21497999 0.98 KDM4E (0.32) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL13267202 0.91 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL18951633 0.88 KDM4E (0.31) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL14037002 0.87 KDM4E (0.40) KDM4ELMNAMAPTATML3MBTL1
SCHEMBL10039123 0.86 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL13113025 0.84 KDM4E (0.31) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL125237 0.84 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL12653898 0.82 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL23739395 0.82 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL13179395 0.81 KDM4E (0.37) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
EP-3591728-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-12-14 — — EP disclosed
EP-3637490-B1 HIGH EFFICIENCY YELLOW LIGHT EMITTERS FOR OLED DEVICES UNIVERSAL DISPLAY CORP (US) 2021-04-21 — — EP disclosed
EP-3470494-A1 OLED COMPRISING ORGANIC COMPOUNDS CONTAINING B-N HETEROCYCLES Universal Display Corporation (US) 2019-04-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 KDM4E 2475/4885MEN1 2086/4885LMNA 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback