SCHEMBL125237

SCHEMBL125237

c1ccc2c(c1)-c1ccccc1C2(c1ccc(Oc2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1)c1ccc(Oc2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ MAPT P10636 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ OPRK1 P41145 1/20 0.42
▸ PTPN1 P18031 1/20 0.38
▸ NTRK1 P04629 2/20 0.36
▸ IGF1R P08069 2/20 0.36
▸ FGFR1 P11362 2/20 0.36
▸ NTRK2 Q16620 2/20 0.36
▸ NTRK3 Q16288 1/20 0.36
▸ SCN9A Q15858 4/20 0.34
▸ ESR1 P03372 1/20 0.34
▸ ESR2 Q92731 1/20 0.34
▸ PDK2 Q15119 1/20 0.33
▸ REN P00797 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25956572 0.92 PTPN1 (0.39) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL10029963 0.92 KDM4E (0.41) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL1334632 0.91 KDM4E (0.52) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL30571079 0.91 KDM4E (0.52) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL29419043 0.91 KDM4E (0.52) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL13172988 0.88 KDM4E (0.37) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL15328898 0.88 KDM4E (0.53) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL126312 0.87 KDM4E (0.47) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL12967881 0.86 ESR1 (0.37) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19595309 0.85 KDM4E (0.32) KDM4EATML3MBTL1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029108-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-02 — — US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 — — US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 — — US disclosed
EP-4329431-A2 NOVEL HETEROLEPTIC IRIDIUM COMPLEXES Universal Display Corporation (US) 2024-02-28 — — EP disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 — — US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 — — US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 — — US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 — — US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 — — US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 — — US disclosed
WO-2010002848-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2010-01-07 — — WO disclosed
US-20090200927-A1 ORGANIC LIGHT EMITTING DEVICE ARCHITECTURE UNIVERSAL DISPLAY CORPORATION (US) 2009-08-13 — — US disclosed
US-20090200927-A1 ORGANIC LIGHT EMITTING DEVICE ARCHITECTURE UNIVERSAL DISPLAY CORPORATION (US) 2009-08-13 — — US disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 — — WO disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 — — US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 — — US disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 — — US disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 — — US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 — — US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 KDM4E 3035/4885ATM 3279/4885L3MBTL1 85/4885
US-12029108-B2 Organic electroluminescent materials and devices LBR, DBF4, DNMT3A KDM4E 770/4885ATM 2032/4885L3MBTL1 229/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 KDM4E 1340/4885ATM 3092/4885L3MBTL1 679/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR KDM4E 2019/4885ATM 2345/4885L3MBTL1 104/4885
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 KDM4E 3635/4885ATM 3627/4885L3MBTL1 111/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L KDM4E 3607/4885ATM 3690/4885L3MBTL1 279/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM KDM4E 4109/4885ATM 2669/4885L3MBTL1 1318/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR KDM4E 2019/4885ATM 2345/4885L3MBTL1 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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