Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.73 |
| ▸ | XDH | P47989 | 7/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20906127 | 0.85 | SLC22A12 (0.75) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL18607457 | 0.85 | SLC22A12 (1.00) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL20906107 | 0.80 | SLC22A12 (0.62) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL22630882 | 0.77 | SLC22A12 (0.78) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL18607472 | 0.77 | SLC22A12 (1.00) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL18607217 | 0.74 | SLC22A12 (1.00) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL18607473 | 0.72 | SLC22A12 (0.78) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL18607464 | 0.72 | SLC22A12 (0.78) | SLC22A12XDHCYP2C8CYP2C9 | |
| SCHEMBL7401479 | 0.72 | CA1 (0.53) | XDHPLAUMAPTCA12CA1 | |
| SCHEMBL13063631 | 0.72 | CA1 (0.53) | XDHPLAUMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344604-B1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-106478500-B | Carboxylic acid substituted (hetero) aromatic ring derivatives, and preparation method and application thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | XDH, ABCG2, SLC7A1 | SLC22A12 314/4885XDH 1/4885EGFR 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.