Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20907014 | 0.93 | CHRM2 (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL726880 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL29440897 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL5151702 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL30200949 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL29459 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL4005011 | 0.90 | BCHE (0.47) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| SCHEMBL20907013 | 0.90 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL2808049 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 | |
| Bepotastine SCHEMBL2803678 | 0.90 | BCHE (0.55) | ADRA1DADRA1AADRA1BDRD2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073486-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF BEPOTASTINE AND ITS BESILATE SALT | METROCHEM API PVT LTD. (IN) | 2019-04-18 | — | — | WO | disclosed |