Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206182 | 0.90 | JAK3 (0.45) | JAK3BRAFCNR2KDRCHEK1 | |
| SCHEMBL20908740 | 0.87 | EGFR (0.52) | JAK3EGFRAURKA | |
| SCHEMBL20908661 | 0.85 | KDR (0.38) | JAK3CNR2KDRCHEK1ALK | |
| SCHEMBL22215290 | 0.85 | KDR (0.44) | JAK3KDRCHEK1CD274FLT3 | |
| SCHEMBL24383588 | 0.83 | CNR2 (0.39) | JAK3HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL28893696 | 0.82 | CHEK1 (0.42) | JAK3CNR2KDRCHEK1ALK | |
| SCHEMBL20908967 | 0.82 | SMN1; SMN2 (0.46) | JAK3HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29743061 | 0.80 | CHEK1 (0.46) | JAK3KDRCHEK1ALKLCK | |
| SCHEMBL23921963 | 0.80 | CHEK1 (0.46) | JAK3KDRCHEK1ALKLCK | |
| SCHEMBL29838449 | 0.80 | KDR (0.44) | JAK3CNR2KDRCHEK1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3696176-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2022-05-04 | — | — | EP | disclosed |
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-10-19 | — | — | US | disclosed |
| EP-3696176-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-08-19 | — | — | EP | disclosed |
| US-20200223821-A1 | Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-16 | — | — | US | disclosed |
| WO-2019074275-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 대웅제약 | 2019-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223821-A1 | Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same | PDCD1, PDCD5, PDCD11 | JAK3 811/4885HDAC3 1607/4885HDAC1 295/4885 |
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DPYD, PDCD5, PDCD1 | JAK3 869/4885HDAC3 1719/4885HDAC1 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.