SCHEMBL20908700

SCHEMBL20908700

Nc1ncnc2c1ncn2[C@H]1C[C@@H]2OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c4ncn4ccnc54)[C@H](F)[C@@H]3OP(=O)(S)OC[C@H]2O1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20908493 1.00 STING1 (0.66) STING1
SCHEMBL20908754 0.94 STING1 (0.72) STING1
SCHEMBL20908472 0.91 STING1 (0.64) STING1
SCHEMBL20908716 0.90 STING1 (0.74) STING1
SCHEMBL20908441 0.90 STING1 (0.74) STING1
SCHEMBL21263826 0.88 STING1 (0.62) STING1
SCHEMBL21263842 0.88 STING1 (0.62) STING1
SCHEMBL23800893 0.86 STING1 (0.78) STING1
SCHEMBL23798614 0.86 STING1 (0.78) STING1
SCHEMBL23800741 0.86 STING1 (0.78) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019074887-A1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2019-04-18 — — WO disclosed
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