SCHEMBL20908716

SCHEMBL20908716

Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]3C[C@H](n4cnc5c4ncn4ccnc54)O[C@@H]3COP(=O)(O)O[C@H]2[C@H]1F

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 19/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20908441 1.00 STING1 (0.74) STING1
SCHEMBL24321884 0.94 STING1 (0.82) STING1
SCHEMBL20908440 0.92 STING1 (0.72) STING1
SCHEMBL26201624 0.92 STING1 (0.87) STING1
SCHEMBL20908708 0.91 STING1 (0.81) STING1
SCHEMBL25691261 0.90 STING1 (0.76) STING1
SCHEMBL24323065 0.90 STING1 (0.76) STING1
SCHEMBL20908700 0.90 STING1 (0.66) STING1
SCHEMBL20908493 0.90 STING1 (0.66) STING1
SCHEMBL21263839 0.88 STING1 (0.69) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019074887-A1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2019-04-18 — — WO disclosed
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