Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880140 | 1.00 | SIGMAR1 (0.46) | SIGMAR1TMEM97AVPR1A | |
| SCHEMBL13366373 | 1.00 | SIGMAR1 (0.46) | SIGMAR1TMEM97AVPR1A | |
| SCHEMBL11396465 | 0.83 | TMEM97 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL11396463 | 0.83 | TMEM97 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL9615977 | 0.83 | SIGMAR1 (0.54) | SIGMAR1AVPR1A | |
| SCHEMBL3400210 | 0.83 | SIGMAR1 (0.46) | SIGMAR1AVPR1A | |
| SCHEMBL13337853 | 0.83 | SIGMAR1 (0.46) | SIGMAR1AVPR1A | |
| SCHEMBL3400212 | 0.83 | SIGMAR1 (0.46) | SIGMAR1AVPR1A | |
| Hydrochloric Acid SCHEMBL11337370 | 0.82 | TMEM97 (0.50) | SIGMAR1TMEM97 | |
| SCHEMBL12964439 | 0.82 | AVPR1A (0.43) | SIGMAR1TMEM97AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074824-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |