Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104652 | 0.82 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL30382126 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL536688 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL130926 | 0.81 | HCRTR1 (0.41) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL22251076 | 0.81 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL536812 | 0.81 | HCRTR1 (0.41) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL536703 | 0.81 | HCRTR1 (0.41) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL20909900 | 0.79 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL29994822 | 0.79 | HCRTR1 (0.40) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL17489106 | 0.79 | PGK1 (0.41) | HCRTR1HCRTR2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |