Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18033538 | 0.80 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6KIF11 | |
| SCHEMBL20883887 | 0.78 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL18034964 | 0.78 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5249510 | 0.78 | SLC6A4 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL20891201 | 0.78 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10957858 | 0.78 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18255846 | 0.77 | SRD5A1 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL18255844 | 0.77 | SRD5A1 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL18255842 | 0.77 | SRD5A1 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL20073096 | 0.76 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |