Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863287 | 0.79 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6SRD5A1 | |
| SCHEMBL22297377 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3SRD5A1 | |
| SCHEMBL20910249 | 0.76 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3CYP2D6KIF11 | |
| SCHEMBL27283990 | 0.71 | KDM4E (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL20924139 | 0.71 | GFRA3 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19879991 | 0.70 | PRF1 (0.32) | — | |
| SCHEMBL21661808 | 0.69 | MAOA (0.39) | SLC6A4CYP2D6KDM4EALDH1A1GLA | |
| SCHEMBL24865825 | 0.68 | MALT1 (0.33) | — | |
| SCHEMBL7489051 | 0.68 | SRD5A1 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6SRD5A1 | |
| SCHEMBL18033538 | 0.68 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2018071836-A1 | COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-04-19 | — | — | WO | disclosed |