Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555142 | 0.84 | HTT (0.71) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1719917 | 0.80 | HTT (0.67) | HTTALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9461214 | 0.80 | HTT (0.67) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL23610342 | 0.78 | HTT (0.64) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL11878004 | 0.78 | HTT (0.64) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL15542709 | 0.76 | HTT (0.61) | HTTPOLBALDH1A1KMT2AMAPT | |
| SCHEMBL1923422 | 0.76 | HTT (0.61) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL30375828 | 0.75 | HTT (0.59) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL5772762 | 0.74 | HTT (0.58) | HTTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL2469053 | 0.72 | HTT (0.56) | HTTPOLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163761-B2 | Methods and compositions for treating disorders | HYDRA BIOSCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |