Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461214 | 0.82 | HTT (0.67) | HTTMAPTKMT2AKDM4EGAA | |
| SCHEMBL23610342 | 0.80 | HTT (0.64) | HTTMAPTKMT2AKDM4EGAA | |
| SCHEMBL2091085 | 0.80 | HTT (1.00) | HTTMAPTKMT2AKDM4EGAA | |
| SCHEMBL1891105 | 0.77 | MAPT (0.46) | HTTMAPTKMT2AKDM4EGAA | |
| SCHEMBL1720487 | 0.76 | NPC1 (0.41) | HTTMAPTKMT2AKDM4ELMNA | |
| SCHEMBL19203818 | 0.75 | ALOX15 (0.45) | HTTMAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL25188346 | 0.74 | HTT (0.43) | HTTMAPTKMT2AKDM4EGAA | |
| SCHEMBL23610343 | 0.73 | HTT (0.55) | HTTMAPTKMT2AKDM4EGAA | |
| SCHEMBL11240594 | 0.72 | MAPT (0.42) | HTTMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL1720666 | 0.72 | CYP1A2 (0.52) | HTTMAPTKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334968-B1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7820861-B2 | chemical intermediate for a sulfonanilide of 4,6-dimethoxypyrmidine derivative herbicide | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| EP-2025665-B1 | Process for producing substituted aniline compound | IHARA CHEMICAL IND CO (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-7531654-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7521555-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7504503-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| EP-2025665-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-7271263-B2 | Process for production of substituted aniline compound | IHARA CHEMICAL INDUSTRY, CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |
| US-20070213561-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213532-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213533-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20060281765-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| US-20040034251-A1 | Process for production of substituted aniline compound | 1HARA CHEMICAL INDUSTRY CO., LT.D. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1334968-A1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034251-A1 | Process for production of substituted aniline compound | NAT1, CBR3, AADAC | HTT 2412/4885MAPT 4460/4885KMT2A 824/4885 |
| US-20070213561-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | HTT 1962/4885MAPT 4368/4885KMT2A 837/4885 |
| US-20060281765-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | HTT 1962/4885MAPT 4368/4885KMT2A 837/4885 |
| US-20070213532-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | HTT 1962/4885MAPT 4368/4885KMT2A 837/4885 |
| US-20070213533-A1 | Process for producing substituted aniline compound | AADAC, NAT1, CBR3 | HTT 1933/4885MAPT 4439/4885KMT2A 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.