SCHEMBL20913050

SCHEMBL20913050

CC(C)(C)OC(C)(C)C.CCCCOCCCC

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CYP3A4 P08684 2/20 0.44
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 1/20 0.38
CES2 O00748 2/20 0.34
CES1 P23141 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1476917 0.84 TSHR (0.43) TSHRCYP3A4MEN1THRBHTT
SCHEMBL9849839 0.83 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL27338598 0.82 HSD17B10 (0.36) TSHR
Hexane SCHEMBL7875362 0.82 TSHR (0.47) TSHRMEN1THRBKMT2ASMN1; SMN2
SCHEMBL8600029 0.82 TSHR (0.71) TSHRCYP3A4MEN1THRBHTT
SCHEMBL439119 0.82 TSHR (0.71) TSHRCYP3A4MEN1THRBHTT
SCHEMBL15167 0.82
SCHEMBL28748446 0.82 TSHR (0.71) TSHRCYP3A4MEN1THRBHTT
Tert-Butanol SCHEMBL6818802 0.80 TSHR (0.62) TSHRCYP3A4MEN1THRBHTT
SCHEMBL27855475 0.80 TSHR (0.62) TSHRCYP3A4MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3472103-A1 LAYERED DOUBLE HYDROXIDES SCG Chemicals Co., Ltd. (TH) 2019-04-24 EP disclosed
CN-101899062-B Synthesis technology of alpha-chiral boric acid and boric acid ester SHANGHAI VIWIT PHARMACEUTICAL CO LTD 2015-04-15 CN disclosed
CN-101899062-A Synthesis technology of alpha-chiral boric acid and boric acid ester VIWIT PHARMACEUTICAL CO LTD 2010-12-01 CN disclosed