Hexane

Hexane

SCHEMBL7875362

CC(C)(C)OC(C)(C)C.CCCCCC

nearest known ligand 0.47

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 3/20 0.40
SLC22A1 O15245 3/20 0.37
SLC22A2 O15244 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DNM1 Q05193 5/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL1554946 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1SLC22A2
Octane SCHEMBL20299932 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
Undecane SCHEMBL28267168 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
Heptane SCHEMBL7940831 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
Dodecane SCHEMBL20299936 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
Heptane SCHEMBL3369680 0.94 TSHR (0.50) TSHRTHRBLMNASLC22A1DNM1
Pentane SCHEMBL12271939 0.90 TSHR (0.47) TSHRTHRBLMNAALDH1A1
Butane SCHEMBL3799640 0.85 TSHR (0.33) TSHRALDH1A1
Water SCHEMBL28300553 0.84 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL20913050 0.82 TSHR (0.52) TSHRTHRBLMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6319876-B1 Microporous amorphous mixed metal oxides for form-selective catalysis STUDIENGESELLSCHAFT KOHLE MBH (DE) 2001-11-20 US disclosed
US-6297180-B1 Microporous amorphous mixed metal oxides for shape selective catalysis STUDIENGESELLSCHAFT KOHLE MBH (DE) 2001-10-02 US disclosed
EP-0054816-B1 PROCESS FOR PREPARING N-PYRROLYL-PYRIDAZINEAMINE DERIVATIVES GRUPPO LEPETIT S.P.A. (IT) 1985-08-07 EP disclosed
US-4385179-A Process for preparing N-pyrrolyl-pyridazineamine derivatives GRUPPO LEPETIT S.P.A. (IT) 1983-05-24 US disclosed
EP-0054816-A1 Process for preparing N-pyrrolyl-pyridazineamine derivatives GRUPPO LEPETIT S.P.A. (IT) 1982-06-30 EP disclosed