Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19874445 | 1.00 | DRD2 (0.33) | DRD2DRD3 | |
| SCHEMBL19874349 | 0.89 | NR1H2 (0.33) | DRD2DRD3 | |
| SCHEMBL19886463 | 0.78 | NR1H2 (0.32) | — | |
| SCHEMBL19874448 | 0.76 | GPER1 (0.32) | DRD2DRD3 | |
| SCHEMBL19874447 | 0.76 | GPER1 (0.32) | DRD2DRD3 | |
| SCHEMBL19874403 | 0.75 | DRD2 (0.33) | DRD2DRD3 | |
| SCHEMBL19874400 | 0.75 | DRD2 (0.33) | DRD2DRD3 | |
| SCHEMBL19874372 | 0.69 | NR1H2 (0.36) | DRD2DRD3 | |
| SCHEMBL19874374 | 0.69 | NR1H2 (0.36) | DRD2DRD3 | |
| SCHEMBL19874306 | 0.68 | GPER1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265465-B1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | AMGEN INC (US) | 2019-04-24 | — | — | EP | disclosed |