Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11152061 | 0.98 | MEN1 (0.76) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL6249805 | 0.98 | MEN1 (0.76) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL3650059 | 0.98 | MEN1 (0.76) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL28063201 | 0.98 | MEN1 (0.76) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL28379483 | 0.96 | MEN1 (0.80) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL28989888 | 0.96 | MEN1 (0.73) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL29281392 | 0.92 | MEN1 (0.65) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL25414352 | 0.92 | LPAR3 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL10638156 | 0.92 | LPAR3 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL10638189 | 0.92 | LPAR3 (0.61) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152844-B1 | MONO-DI-AND POLYOL PHOSPHATE ESTERS IN PERSONAL CARE FORMULATIONS | SOLVAY USA INC (US) | 2019-04-24 | — | — | EP | disclosed |