Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071618 | 0.79 | ADA (0.57) | SLC29A1ADAADK | |
| SCHEMBL2578051 | 0.79 | SLC29A1 (0.47) | SLC29A1ADA | |
| SCHEMBL11081361 | 0.79 | ADA (0.57) | SLC29A1ADAADK | |
| SCHEMBL5508294 | 0.79 | ADA (0.57) | SLC29A1ADAADK | |
| SCHEMBL10335631 | 0.79 | ADA (0.57) | SLC29A1ADAADK | |
| SCHEMBL12174029 | 0.79 | SLC29A1 (0.47) | SLC29A1ADA | |
| SCHEMBL23982307 | 0.78 | PRMT5 (0.47) | PRMT5WDR77SLC29A1ADK | |
| SCHEMBL20938420 | 0.78 | ADK (0.58) | PRMT5WDR77ADK | |
| SCHEMBL1738432 | 0.78 | ADK (0.58) | PRMT5WDR77ADK | |
| SCHEMBL20938183 | 0.78 | ADK (0.58) | PRMT5WDR77ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697800-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | Universiteit Gent (BE) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |