Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600500 | 0.84 | HTT (0.42) | HTTNPSR1NPC1HPGDMAPK1 | |
| SCHEMBL28497299 | 0.83 | ALDH1A1 (0.41) | HTTHPGDTYRESR1ESR2 | |
| SCHEMBL8585742 | 0.82 | HPGD (0.43) | HTTNPSR1NPC1HPGDMAPK1 | |
| SCHEMBL8891283 | 0.82 | TYR (0.49) | HTTHPGDTYRESR1ALDH1A1 | |
| SCHEMBL11660171 | 0.82 | TYR (0.49) | HTTHPGDTYRESR1ALDH1A1 | |
| SCHEMBL11202288 | 0.82 | TYR (0.49) | HTTHPGDTYRESR1ALDH1A1 | |
| SCHEMBL27822394 | 0.81 | HPGD (0.46) | HTTNPSR1NPC1HPGDMAPK1 | |
| SCHEMBL7950540 | 0.81 | TYR (0.53) | HTTNPSR1NPC1HPGDMAPK1 | |
| SCHEMBL7913919 | 0.79 | ALDH1A1 (0.48) | HTTNPSR1NPC1HPGDMAPK1 | |
| SCHEMBL11340841 | 0.79 | SKP2 (0.43) | HTTNPSR1NPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697835-A1 | FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS | Clariant Plastics & Coatings Ltd (CH) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076688-A1 | FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS | CLARIANT PLASTICS & COATINGS LTD (CH) | 2019-04-25 | — | — | WO | disclosed |