SCHEMBL20922103

SCHEMBL20922103

Cc1ccc(C(=O)Nc2cccc(F)c2)cc1C

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 3/20 0.65
KCNK9 Q9NPC2 2/20 0.65
NPC1 O15118 6/20 0.65
RAB9A P51151 6/20 0.65
HPGD P15428 2/20 0.65
KMT2A Q03164 7/20 0.61
MEN1 O00255 6/20 0.61
TSHR P16473 1/20 0.60
CNR1 P21554 1/20 0.60
MAOB P27338 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
BRAF P15056 1/20 0.56
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16302670 0.90 KMT2A (0.77) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL22025010 0.87 KCNK3 (0.60) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL22065286 0.86 BRAF (0.60) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL23657758 0.85 NPC1 (0.64) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL22065295 0.85 KCNK3 (0.58) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL12847636 0.84 KMT2A (0.76) KCNK3KCNK9NPC1RAB9AKMT2A
SCHEMBL19156982 0.83 KCNK3 (0.91) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL18160357 0.83 KMT2A (0.65) NPC1RAB9AKMT2AMEN1MAOB
SCHEMBL22025348 0.83 CNR1 (0.55) KCNK3KCNK9NPC1RAB9AHPGD
SCHEMBL22024522 0.83 CNR1 (0.55) KCNK3KCNK9NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3473624-B1 NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) 2022-05-11 EP disclosed
EP-3473624-A1 NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2019-04-24 EP disclosed