Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636464 | 0.91 | MAOA (0.64) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL13480197 | 0.89 | TDP1 (0.58) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL22162594 | 0.89 | TDP1 (0.67) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL17471899 | 0.88 | MAOA (0.59) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL15858238 | 0.86 | TDP1 (0.63) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL12085493 | 0.86 | MAOA (0.56) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL24275903 | 0.85 | MAOA (0.51) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL20542889 | 0.85 | TDP1 (0.61) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL12160128 | 0.85 | TDP1 (0.61) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL5267898 | 0.85 | TDP1 (0.61) | MAOAMAOBTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473247-A1 | COMPOSITION FOR ORAL DELIVERY COMPRISING MGBG FOR USE IN TREATING MULTIPLE SCLEROSIS | Pathologica LLC (US) | 2019-04-24 | — | — | EP | disclosed |