Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112595 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL24230540 | 0.74 | CA1 (0.41) | — | |
| SCHEMBL19370703 | 0.72 | — | — | |
| SCHEMBL19606232 | 0.68 | — | — | |
| SCHEMBL21208081 | 0.65 | — | — | |
| SCHEMBL3116666 | 0.65 | — | — | |
| SCHEMBL18904221 | 0.65 | — | — | |
| SCHEMBL11852334 | 0.65 | TSHR (0.37) | TSHR | |
| SCHEMBL19302203 | 0.64 | PDF (0.30) | — | |
| SCHEMBL25796677 | 0.64 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327013-B1 | 5-SUBSTITUTED ISOINDOLINE COMPOUNDS | CELGENE CORP (US) | 2019-04-24 | — | — | EP | disclosed |