Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923189 | 0.97 | AR (0.41) | ARIMPDH2METAP2LMNACYP2C19 | |
| SCHEMBL20924111 | 0.96 | AR (0.39) | ARIMPDH2METAP2LMNACYP2C19 | |
| SCHEMBL19909346 | 0.95 | AR (0.40) | ARIMPDH2METAP2LMNACYP2C19 | |
| SCHEMBL20923517 | 0.94 | AR (0.39) | ARIMPDH2METAP2LMNACYP2C19 | |
| SCHEMBL20924030 | 0.94 | PDE10A (0.37) | LMNACYP2C19HPGDKDM4EPDE5A | |
| SCHEMBL20924125 | 0.93 | AR (0.41) | ARIMPDH2METAP2LMNACYP2C19 | |
| SCHEMBL20923190 | 0.92 | AR (0.38) | ARIMPDH2METAP2LMNACYP2C19 | |
| SCHEMBL19913205 | 0.92 | AR (0.42) | ARMETAP2LMNACYP2C19HPGD | |
| SCHEMBL20923655 | 0.91 | TDP1 (0.35) | METAP2LMNACYP2C19HPGDKDM4E | |
| SCHEMBL20923089 | 0.91 | IMPDH2 (0.38) | IMPDH2LMNACYP2C19HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |