SCHEMBL20923243

SCHEMBL20923243

Cc1cc(C#N)c(-c2ccncc2)cc1-n1c2ccc(-n3c4ccccc4c4ccccc43)cc2c2cc(-n3c4ccccc4c4ccccc43)ccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.36
LMNA P02545 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP2C19 P33261 2/20 0.36
PDE3B Q13370 2/20 0.36
PDE3A Q14432 2/20 0.36
PDE5A O76074 1/20 0.36
TSHR P16473 1/20 0.36
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
BLM P54132 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SQOR Q9Y6N5 1/20 0.34
METAP2 P50579 1/20 0.34
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20923641 1.00 HPGD (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20923587 0.96 SQOR (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20924102 0.96 SQOR (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20923235 0.94 HPGD (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20923233 0.94 HPGD (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL19908986 0.91 SQOR (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL19908978 0.91 SQOR (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20923135 0.90 KDM4E (0.39) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20923536 0.89 CYP11B1 (0.36) HPGDLMNAKDM4ECYP2C19PDE3B
SCHEMBL20923624 0.89 SQOR (0.36) HPGDLMNAKDM4ECYP2C19PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266772-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-04-24 EP disclosed