Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.69 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924041 | 0.82 | KDM1A (0.69) | KDM1ADHODHPDE2APDE10AESR2 | |
| SCHEMBL526737 | 0.82 | KDM1A (1.00) | KDM1A | |
| SCHEMBL526738 | 0.82 | KDM1A (1.00) | KDM1A | |
| SCHEMBL7701598 | 0.82 | KDM1A (1.00) | KDM1A | |
| Hydrochloric Acid SCHEMBL528304 | 0.81 | KDM1A (0.97) | KDM1A | |
| Hydrochloric Acid SCHEMBL528303 | 0.81 | KDM1A (0.97) | KDM1A | |
| SCHEMBL20924009 | 0.73 | KDM1A (0.69) | KDM1ADEGS1 | |
| SCHEMBL20019597 | 0.73 | KDM1A (0.68) | KDM1AKDM4E | |
| SCHEMBL20924356 | 0.72 | KDM1A (0.66) | KDM1ADHODHKDM4E | |
| SCHEMBL20924051 | 0.70 | KDM1A (0.53) | KDM1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |