Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924090 | 0.97 | CYP19A1 (0.38) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL20923834 | 0.96 | CYP11B1 (0.40) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL20924122 | 0.93 | FLT3 (0.38) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL20923546 | 0.92 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2FLT3MAPK13 | |
| SCHEMBL20923144 | 0.92 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL20923767 | 0.92 | PIK3CA (0.40) | CYP19A1CYP11B1CYP11B2FLT3MAPK13 | |
| SCHEMBL20923142 | 0.91 | CYP19A1 (0.38) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL19909297 | 0.91 | STS (0.38) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL22170341 | 0.90 | FLT3 (0.40) | CYP19A1CYP11B1CYP11B2STSFLT3 | |
| SCHEMBL20923146 | 0.90 | GSK3A (0.39) | CYP19A1PIK3CACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |